Difference Between Monophasic And Biphasic Liquid Dosage Form

Monophasic and biphasic liquid

The monophasic dosage form is a single-phase system consisting of two or more components.This is represented by the true solution and the true solution is a clear homogeneous mixture prepared by dissolving the solute in an appropriate solvent. A biphasic system consists of a solid dispersed state and a liquid continuous phase that can be aqueous or oily and is stabilized by the addition of a suspended agent.

Read Also: Monophasic liquid overview

Difference Between Monophasic And Biphasic Liquid

1. The major difference between monophasic and biphasic liquid dosage forms is that the monophasic liquid dosage forms have a single homogeneous phase, whereas biphasic liquid dosage forms consist of two distinct phases. Both forms include at least one drug in formulation, monophasic forms are homogeneous and completely dissolve in liquid, whereas biphasic forms are not dissolved in a vehicle.

2. In a clear solution, there is no need to shake the bottle unlike a biphasic liquid that will settle down and require shaking to redisperse

Read Also: Classification of Biphasic liquid

3. Monophasic provide consistent dose than biphasic liquid form

4. Monophasic liquid does not require suspending agents but biphasic liquid can only work in the presence of a good suspending agent