Cyproheptadine Weight Gain

Cyproheptadine is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. It is used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes/nose, sneezing, hives, and itching. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.

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Cyproheptadine is the main active pharmaceutical ingredient (API) in weight gain products. This is because one of the side effects include appetite stimulants and drowsiness. Both contribute to weight gain.

Cyproheptadine cause weight gain as side effects
Cyproheptadine tablet

Cyproheptadine Weight Gain Side Effect

In theory, cyproheptadine may stimulate appetite by raising levels of IGF-1 and acting on the area of your brain that controls appetite and food intake. Drowsiness was a common transient side effect of cyproheptadine. This is due to stimulation of growth hormone secretion by deep sleep induction.

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Stimulation of appetite will lead to consuming more food. Food that sometimes adds to body weight. Food alone will not lead to weight gain if not accompanied by proper rest. And that is where drowsiness comes into play. Users find out that they sleep more at home than usual. More food and more rest result in weight gain.

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