Advantage And Disadvantage Of Pharmaceutical Solution

Solutions are homogeneous mixtures of one or more solutes molecularly dispersed in a suitable solvent or a mixture of mutually miscible solvents. Pharmaceutical solution with medication as part of the solutes.

Pharmaceutical solution

Pharmaceutical solutions are used for many routes of administration, including oral, rectal, vaginal, ophthalmic, parenteral, and otic. The most common solution dosage form is the oral liquid, which includes aqueous solutions, syrups, and elixirs.

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Drugs are commonly given in solution in cough/cold remedies and in medications for the young (pediatric) and elderly (geriatric).

Advantages Of Pharmaceutical Solutions

1. The drug is immediately available for absorption

2. Flexible dosing is possible

3. Solutions are designed for any route of absorption

4. No need to shake the container

5. Facilitate swallowing in difficult cases (e.g. infants or the elderly)

6. Safe means of administering substances like potassium iodide and bromide that cause gastric pain if taken dry.

7. Attractive appearance adds to patient compliance

Disadvantages Of Pharmaceutical Solutions

1. Drug stability is reduced

2. It is difficult to mask unpleasant tastes

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3. They are much larger & more bulky, and difficult to transport. Liquids packed in glass bottles are obviously prone to breakage and cause loss of the preparation

4. Technical accuracy is needed to measure the dose on administration

5. Some drugs are poorly soluble so it is necessary to alter vehicle or drug form in order to formulate a convenient preparation

6. A measuring device is needed for administration so need to be supplied to the patient to be able to measure an accurate dose

7. These are seldom formulated for long life because they are mainly prescribed for acute conditions like cough, diarrhea and constipation etc.