Overview Of Pharmaceutical Structure Wise Tablet
Pharmaceutical comes in superior structure. The formation is designed to exhibit some characteristics.
Structure wise tablet |
a) Divisible Tablet
It is sometimes necessary to administer one-half or one-fourth of a tablet and under such circumstances tablets are generally scored once in the middle or twice with lines perpendicular to one another. V-shaped double layer tablets with scoring in the center has been designed.
Read Also: Overview Of Pharmaceutical Targeted Tablet
In cases like this, the tablet may have all its contents evenly distributed. Dividing along the lines provided will produce an exact amount of content.
Advantage Of Divisible Tablet
1. Cheaper as a single tablet can serve more than one person or multiple dose
Disadvantage Of Divisible Tablet
1. Broken or split tablet may be expose to external environment which may not be stable for long
b) Aperture Tablets
Designed with a view to achieve constancy in the surface area during disintegration and dissolution. In this tablet, an equal amount of the drug is undergoing disintegration at any point in time. Design for sucking.
Read Also: Types And Classification Of Pharmaceutical Tablet
Advantage Of Aperture Tablet
1. Even rate of absorption which reduce toxic levels and constant release of drug
Disadvantage Of Aperture Tablet
1. Bitter tasting drugs cannot be formulated
c) Concave-convex Tablets
These tablets have been designed with a view to keep the surface area of the structure relatively constant during the dissolution process. Area is lost on the convex surfaces and gained at the concavities. Commonly deployed in drugs for sucking.
Advantage Of Concave-convex Tablet
1. Even disintegration and dissolution preventing toxic levels
2. Palatable tablet
Read Also: Overview Of Pharmaceutical Multiple Compressed Tablet
Disadvantage Of Concave-convex Tablet
1. Design tablet for sucking with this shake are difficult to suck
2. Bitter tasting drugs cannot be formulated
d) Core Tablets
These tablets have a central core over which another layer of material is compressed and are generally made by two successive compressions. Separate incompatible ingredients.
Advantage Of Core Tablet
1. Incompatible active pharmaceutical ingredient can be formulated into a single tablet
2. Encourage adherence as oppose to multiple tablet
Disadvantage Of Core Tablet
1. Expensive
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