Advantage And Disadvantage Of Rectal Medication
Medications administered per rectum (PR) are ideal for local or systemic treatment, as the rectal mucosa has a blood and lymph supply that is capable of effective systemic absorption. Medication intended for rectal administration often comes in the form of a suppository or an enema. Suppositories are small, torpedo-shaped pellets that melt at body temperature, whereas enemas are substances in liquid form designed for rectal administration. Rectal Medication The rectum constitutes the final 20cm or so of the terminal gastrointestinal tract; approximately 2-3cms of this is the anal canal. Absorption from within the anal canal is via its highly vascular mucous membrane that is divided into folds or pillars, known as anal columns. Rectal epithelium is composed of non-keratinized and villi-free cells. This provides approximately 200 - 400 cm³ surface area for absorption. Read Also : Advantage And Disadvantage Of Sublingual/Buccal Medication The anal canal is divided into areas above an...
