Preparation And Production Of Pharmaceutical Powder
Mixing of pharmaceutical powder is a unit operation that serves to make two or more components uniformly distributed in the powder bed. The mixing process is necessary to ensure that the active pharmaceutical ingredient (API) and other components are homogeneously distributed throughout the tablet. Pharmaceutical powder Powders do not mix spontaneously; therefore, effective mixing requires a thorough understanding of the materials to be mixed, as well as the science of mixing. Effective mixing of powders poses the greatest challenge when the amount of one of the components of the mix is relatively small compared to the other components. Mechanisms Involved In The Mixing Of Pharmaceutical Powder There are three main mechanisms involved in the mixing process, related to the different kinds of particle motion. These include: 1. Convection 2. Shear 3. Diffusion Preparation Of Pharmaceutical Powder 1. Reduction of particle size of all ingredients to the same range to prevent stratification ...
