Overview, Advantage And Disadvantage Of Pharmaceutical Rectal Tablet
The rectal tablet can be considered a good alternative to the oral tablet for the paediatric population because these dosage forms are neither to be swallowed nor need to be taste-masked. It is an old and acceptable means of treatment. The volume and nature of rectal fluid, its buffer capacity, pH and surface tension play a large part in this but are subject to wide variation, even within a single subject, resulting in variability of absorption by this route. Rectal tablets have both systemic and local effects. Rectal tablet Rectal Tablet Composition Rectal tablets are composed of solid supports impregnated with medicinal substances. They are solid dosage forms containing drugs that are either dispersed or dissolved in a suitable lipophilic base or hydrophilic base. Read Also: Difference Between Suppository And Enema Lipophilic bases are immiscible with body fluids and readily melt at body temperature to release the drug on the mucosal surface, whereas hydrophilic bases need to d...
