Overview Of Pharmaceutical Dispersible Tablet
Dispersible tablets (DT) as defined in European Pharmacopoeia are uncoated or film coated tablets containing active pharmaceutical ingredients (API) intended to be dispersed in water before administration giving a homogeneous dispersion. They disintegrate either rapidly in water to form stabilized suspension or disperse instantaneously in the mouth to be swallowed without the aid of water. Typically a dispersible tablet is dispersed in about 5 to 15 ml of water (e.g. in a tablespoonful or a glass of water) and the resulting dispersion is administered to the patient. Dispersible tablets are required to disintegrate within 3 min in water at 15 to 25. Also the dispersion produced from a dispersible tablet should pass through a sieve screen with a nominal mesh aperture of 710 µm. Dispersible tablet Orodispersible tablets (ODTs) are distinguished from classic sublingual tablets, which take more than a few minutes to dissolve in the oral cavity. Orodispersible tablets, quick disintegrating t...
