Overview Of Pharmaceutical Modified Release Tablet
Modified-release tablets are coated, uncoated, or matrix tablets containing excipients or prepared by procedures which, separately or together, are designed to modify the rate, the place or the time of release of the active ingredient(s) in the gastrointestinal tract. They release the medication slowly for a long time after administration of a single tablet. Used to target the site specific releases. Modified release tablet Comparison of blood concentration vs. time any adjuvant that can alter water uptake rate, swelling, and gelling characteristics can alter the release rate of API. The drug release can be modified by providing suitable microenvironment pH in the tablet. Inclusion of alkaline polymers results in desirable drug release of acidic drugs. Read Also: Types And Classification Of Pharmaceutical Tablet M/R preparations may be prescribed to: • reduce the dosing frequency and improve patient compliance; • reduce fluctuations (peaks and troughs) in drug plasma concentration...
