Overview Of Transdermal Drug Administration
Transdermal drug delivery system is defined as the topically administered medications in the form of patches which when applied to the skin deliver the drug, through the skin at a predetermined and controlled rate. This increases the therapeutic efficacy of the drug and reduces the side effects of the drug. Skin is an effective medium from which absorption of the drug takes place and enters the circulatory system. Transdermal formulation maintains drug concentration within the therapeutic window for a prolonged period of time ensuring that drug levels neither fall below the minimum effective concentration nor exceed the maximum effective concentration. Transdermal Anatomy Of The Skin There are two important layers to the human skin: (1) the Epidermis and (2) the Dermis. For transdermal delivery, drugs must pass through the two sublayers of the epidermis to reach the microcirculation of the dermis. Read Also: Types Of Topical Medication The skin’s outermost layer called stratum co...
