Nolvadex Versus (Vs) Clomid For Male Fertility

Nolvadex and clomid are drugs with different uses and indications. They are both anti-estrogen.

Nolvadex (tamoxifen) is a selective estrogen receptor modulator used to prevent breast cancer in women and treat breast cancer in women and men.

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Clomid (clomiphene citrate) is a drug used for male fertility treatment. It is a non-steroidal fertility medicine. It causes the pituitary gland to release hormones needed to stimulate ovulation (in women), and increase testosterone level and improve sperm count (in men).

Clomid

The administration of anti-oestrogens is a common treatment currently tested in most countries. This is because anti oestrogens interfere with the normal negative feedback of sex steroids. This happens at the hypothalamic and pituitary levels in order to increase endogenous gonadotropin-releasing hormone secretion from the hypothalamus and FSH and LH secretion directly from the pituitary. In turn, FSH and LH stimulate Leydig cells in the testes, and this has been claimed to lead to increased local testosterone production, thereby boosting spermatogenesis with a possible improvement in fertility.

Nolvadex Vs Clomid

Individually, both drugs showed some level of activity on testosterone level. Further trials failed to show an increase in pregnancy level compared to placebo.

Nolvadex and clomid have a lot of side effects. However, the majority of these side effects are minor. But men using Nolvadex and clomid and wanting a baby may have to think twice.

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Nolvadex cause loss of sexual ability/interest in men. This can cause infertility which results may not lead to pregnancy since the desire for sex is out. The likely solution is artificial insemination, invitro and invivo fertilization.

But if you want to opt in for the one with the milder effect on libido, nolvadex will be better. Clomid have more effect on lower libido than nolvadex.

Nolvadex And Clomid Combination

There are no official interaction between both. However, they may not be suitable to be used together.