Overview Of Pharmaceutical Multiple Compressed Tablet
Multiple compressed tablets are prepared by more than one compression cycle. This process is best suited when separation of active ingredient is needed for stability purposes, or if the mixing process is inadequate to guarantee uniform distribution of two or more active ingredients. They are usually prepared to separate physically or chemically incompatible ingredients or to produce repeat or prolonged action of drugs. They are also known as multiple layered tablets or a tablet within the tablet. Multiple compressed tablets There are three categories under this class: compression coated tablets, inlay tablets and layered tablets. Multiple compression tablets, especially layered tablets, tend to solve incompatibility issues between two or more active pharmaceutical ingredients (APIs). Bilayer tablet provides adequate surface separation of two reactive ingredients but there may be some reactivity at the interface. If complete physical separation is required for stability purposes then th...
