DrugXpert Blog

Both typhoid and malaria share social circumstances which are imperative to their transmission. They are treatable with many drugs available for both young and old, men and women including pregnant women. People living in Nigeria are at risk of contracting both these diseases, either concurrently or an acute infection superimposed on a chronic one. A high index of suspicion is necessary to diagnose a co-infection as most clinicians are used to linking every symptom and sign to a single pathology. Mosquito Typhoid Fever Typhoid fever is a life-threatening infection caused by the bacterium Salmonella Typhi. It is usually spread through contaminated food or water. Once Salmonella Typhi bacteria are eaten or drunk, they multiply and spread into the bloodstream. Read Also :  Treatment of typhoid Symptoms include prolonged high fever, fatigue, headache, nausea, abdominal pain, and constipation or diarrhoea. Some patients may have a rash. Severe cases may lead to serious complications or ...

Direct compression (DC) is a popular choice because it provides the shortest, most effective and least complex way to produce tablets. The manufacturer can blend an API(s) with the excipient(s) and the lubricant, followed by compression, which makes the product easy to process. No additional processing steps are required. Granulating machine Direct compression formulations can be developed with minimal numbers of excipients. Typically the minimum excipients needed are a diluent (filler binder), a disintegrant and a lubricant. Additional components may include a glidant, a surfactant, pigments and stabilising agents. It does require a very critical selection of excipients in comparison to granulation processes because the raw materials must demonstrate good flowability and compressibility for successful operation. Moisture or heat sensitive ingredients, which would be contraindicated in wet granulation, can also be used in this type of process. Read Also :  Manufacture of pharmaceut...

Uterine fibroids (leiomyomas or myomas), benign monoclonal tumors, are the most common benign tumors in women of childbearing years. The cause of fibroids is not well understood. Risk factors include a family history of fibroids, obesity or early onset of puberty. Read Also :  The benefits coconut water has for children Coconut Water And Fibroid Young coconut water is another natural supplement that has a high level of estrogen. Per traditional knowledge, Thais believe that drinking young coconut water while menstruating will cause menstruation to stop or become sporadic as well as delay the next cycle. Coconut water While the cause of uterine fibroid tumors is still unknown, there is a link between fibroids and estrogen production. For instance, fibroids can grow large during pregnancy when estrogen levels are high, and can begin to shrink during menopause, when estrogen levels are low. Read Also :  Effect of drinking hot water on fibroid If estrogen levels are too high, it c...

Drink hot water to shrink that fibroid says some persons. I wonder who started it and why it is gaining popularity among women with fibroid. To find out if drinking or even bathing with hot water can shrink fibroid, let's us take a look at fibroid itself. What Is Fibroid Uterine fibroids (leiomyomas or myomas), benign monoclonal tumors, are the most common benign tumors in women of childbearing years. The cause of fibroids is not well understood. Risk factors include a family history of fibroids, obesity or early onset of puberty. Fibroid Symptoms Of Uterine Fibroid Heavy or prolonged menstrual bleeding, abnormal uterine bleeding, resultant anemia, pelvic pain, infertility, and/or recurrent pregnancy loss are generally associated with uterine fibroids. Read Also :  Ruzu bitters for the shrinking of fibroid Although curative treatment of this tumor relies on surgical therapies, medical treatments are considered the first-line treatment to preserve fertility and avoid or delay surger...

Granulation is a process where primary powder particles are blended and adhered to form larger, multiparticle entities called granules. Most of the drug substances do not carry the desired properties that would give a satisfactory flow from the hopper to the die cavity of tablet presses. Thus, they are run through pretreatment alone or with suitable excipients to produce free-flowing granules that are easily available for tabletting. Granules Granulation is used to improve processability of solids, control dissolution profiles of a drug and eliminate poor content uniformity in final dosage forms. It’s often the first processing step when multiple formulation components are combined. Read Also :  Types of pharmaceutical excipient Tablets are generally manufactured by three processes, namely, wet granulation, dry granulation or direct compression. These processing methods involve several steps or unit processes like weighing, milling, mixing, granulation, drying, compaction, coating ...

The wet granulation process is the traditional method of manufacture and is frequently used in the pharmaceutical industry. Expertise in wet granulation is widely available, as in the required equipment. Granules The process improves flow and cohesion, reduces dust and cross contamination and permits the handling of powder blends without loss of homogeneity. High-speed mixer-granulators, fluidized bed granulation and drying and an ever increasing use of automation have served to make wet granulation a much more efficient and economic process than it once was. Read Also :  Overview of wet granulation of powder in tablet manufacture Advantage Of Wet Granulation 1. Granules form are more spherical than the powder, hence has better flow properties, and suitable for different types of dissolution rates. 2. The wet granulation process improves the flowability, compressibility, and cohesiveness of the powder. This allows the use of low pressure during compression and reduces machine wear ...

Wet granulation is a process of dry mixing, wet mixing, and particle size enlargement, and is a process of particle attachment (agglomeration). Wet granulation techniques consist of homogeneously mixing the active pharmaceutical ingredient (API) with other powder excipients and wetting them in the presence of a binder or granulating fluid, forming larger agglomerates/granules. The wet granules are dried to remove moisture and then either screened or milled to eliminate oversized agglomerates and to control the particle size distribution. Granules Wet granulation is a complex process with a combination of several critical formulation and process variables greatly affecting the outcome. For example, determination of the granulation endpoint is still considered by many to be a fine art, requiring knowledge gained through years of hands-on experience. The window for liquid addition can be very narrow and over-wetting of powder can lead to the entire batch being completely unusable. Read Al...

Granulation has got lots of advantages more than disadvantages and that is why it is popular in pharmacy today. Granulation process is an inevitable step in tablet manufacturing as it improves flow property and compressibility of powder mass intended for compression. Granulation prevents segregation of the constituents of the powder mix. Granules Granulation is the process in which primary powder particles are made to adhere to form larger, multi-particle entities called granules. Pharmaceutical granules typically have a size range between 0.2 and 4.0 mm, depending on their subsequent use. Read Also:   Type of tablet that can be broken into half and still be effective Advantage Of Granulation 1. To enhance powder flow and powder handling 2. Degrease segregation of the powder components 3. To produce “dust free” formulations 4. Improve compressibility of the material 5. To increase the uniformity of drug distribution in the product 6. To densify the material 7. Optimise dissolution ...

Africans have been using bitter kola for pregnant women since ages. Nowadays, bitter kola popularity has spread worldwide. bitter kola Bitter kola, also known as bitter cola or Garcinia Kola, is a plant found in Central and Western Africa that has long been valued for its medicinal properties. Although traditional African medicine uses all parts of the Bitter Kola plant, the seeds are mostly commonly eaten. Read Also :  Effects of Ruzu herbal bitters on pregnancy Benefits Of Bitter Kola In Pregnancy Drinking bitter kola is good for pregnancy. Bitter kola contains nutrients and vitamins good for pregnancy. For Africans, bitter kola is the best supplement for pregnant women. Health benefits of bitter kola include treating nausea and vomiting, making the uterus healthier, strengthening pregnant women and normalizing blood circulation in pregnant women. Untoward Effects Of Bitter Kola In Pregnancy Using very high doses of bitter kola is not recommended. A very high dose of bitter kola ...

Clotrimazole is a drug which is used to treat vaginal yeast infections. It reduces vaginal burning, itching, and discharge that may occur with this condition. This medication is an azole antifungal. It works by stopping the growth of yeast (fungus) that causes the infection. The vaginal product comes in 2 forms (a vaginal cream or tablet). Clotrimazole Should I Remove Clotrimazole Cream Or Tablet After Insertion Some girls attempt to remove clotrimazole cream or tablets that they have inserted. They do it with the belief that the tablet has done its work and they want the solid out of their system. Read Also:  Peeing after inserting clotrimazole Clotrimazole cream or tablets are designed to be inserted into the vagina and absorbed into the body. It melts at body temperature, dissolves and subsequently is absorbed. The whole process takes between 15 minute to an hour. The absorption of clotrimazole is necessary for it to work. It will not be absorbed into the body if the tablet does...

The advantage and disadvantage of dry granulation process is based on the other two granulation techniques; wet granulation and direct compression. Dry granulation is a powder agglomeration process used in the pharmaceutical industry to improve the flowability of powders by increasing the particle size (granules). This operation is achieved using a roller press, which can have different configurations and equipment designs. Read Also:  Production of pharmaceutical tablet Dry Granulation Process When the granulated ingredients are sensitive to moisture or heat, this procedure is implemented. Granules are produced without the aid of any liquid solution as the name suggests. This technique is used for the preparation of aspirin and other aspirin combinations for tablets. Dry granulation machine The steps involved in dry granulation are- weighing formulation ingredients, mixing of formulation ingredients, compression of mixed powders into slugs, milling, and sieving of slugs, mixing wi...

Tablet manufacture involves granulation. There are three types of granulation. In this post, we will focus on dry granulation. Dry granulation of tablet Definition Of Dry Granulation Dry granulation is a process whereby granules are formed without the aid of any liquid solution. The process is used if the ingredients to be granulated are sensitive to moisture or heat. Compaction is used to densify the powder and form granules. Read Also :  General properties of pharmaceutical tablet Dry granulation, also referred to as precompression or double compression, is a size enlargement process designed to improve the flow and compression characteristics of powders that would otherwise be unsuitable for compression. The process involves compaction of powder particles into large pieces or compacts which are subsequently broken down into granules to produce granules that can be further processed into dosage forms. Reason For Dry Granulation Dry granulation is used in the manufacture of tablet...

Clotrimazole is a drug which is used to treat vaginal yeast infections. It reduces vaginal burning, itching, and discharge that may occur with this condition. This medication is an azole antifungal. It works by stopping the growth of yeast (fungus) that causes the infection. The vaginal product comes in 2 forms (a vaginal cream or tablet). Clotrimazole Can You Pee After Inserting Clotrimazole I get this question a lot. The question is not very straightforward. Clotrimazole insertion does not prevent you from peeing. So you can pee after inserting clotrimazole. Read Also:  How long for clotrimazole to dissolve after insertion But you should not pee immediately after insertion. Although the urethra is outside or front of the vagina, some of the urine will go inside the vagina. This can dissolve the clotrimazole too fast and make it too watery. The drug can start leaking out. It takes about 15 minutes for the clotrimazole tablet to dissolve and another 45 to be absorbed. Within this h...

For clotrimazole tablet or cream to start to dissolve, it must be inserted into the body orifice. After insertion, it will then dissolve. This takes some time depending on the dosage form be it tablet or cream. Absorption of clotrimazole tablet or cream after it has dissolve is the same. Clotrimazole is a drug which is used to treat vaginal yeast infections. It reduces vaginal burning, itching, and discharge that may occur with this condition. This medication is an azole antifungal. It works by stopping the growth of yeast (fungus) that causes the infection. The vaginal product comes in 2 forms (a vaginal cream or tablet). Clotrimazole How Long For Clotrimazole To Dissolve And Absorb Vagina suppositories are made to dissolve at body temperature. They achieve this with the aid of base added to the drug. After dissolving, they are absorbed into the body. Read Also:   Advantage and disadvantage of topical medication Clotrimazole bases are made from substances like gelatin or cocoa but...

Apetito is a drug containing cyproheptadine. Cyproheptadine is an antihistamine use for itching, running nose, etc. One of the side effects is appetite stimulant. Apetito is very common in Zimbabwe and some other Africa countries. Apetito tablet Apetito Tablet Composition Each tablet contains cyproheptadine HCl 4mg Side Effects Of Apetito Tablet Drowsiness, tired feeling, sleep problems (insomnia), dizziness, spinning sensation, blurred vision, loss of coordination, upset stomach, nausea, diarrhea, constipation, appetite changes, weight gain, restlessness or excitability (especially in children), numbness or tingly feeling, increased sweating or urination, thickening of mucus in the nose/throat, or dry mouth/throat/nose. Apetito Cause Infertility There is no scientific study or research that has linked both female or male infertility to apetito. Apetito does not cause low libido, low sperm count and erectile dysfunction. Read Also : All about apetamin Apetito For Hips And Bums Many peo...

There is a list of antenatal drugs. They are also called prenatal vitamins. They are routine drugs given to pregnant women. They have different functions. Pregnant woman Food alone may not be able to provide all the vitamin needs of a pregnant woman or adequate enough. The major reason for antenatal drugs is to supplement food vitamin and mineral and eventually prevent miscarriage, prevent birth defect and protect the mother. Pregnant women who fail to take them stand a higher risk of any of the above. Read Also:  Everything about antenatal care (ANC) in Nigeria hospital In the hospital, pregnant women who attend antenatal or clinics are placed on routine drugs. There are five routine drugs given to pregnant women in Nigerian hospitals. Let us take a look at them and why they are important. List Of Routine Antenatal Drugs Iron/Fesulf/Ferrous Sulphate Iron is one of the building blocks of red blood cells (RBC). The RBC if pregnant women double. So they need to make extra RBC. The on...

Hovid Neurovit and Neurovit forte tablets are manufactured with pharmaceutical standards. They both contain the 3 main vitamins B, B1 (thiamine), B6 (Pyridoxine) and B12 (Cyanocobalamin). Neurovit forte tablet Neurovit and Neurovit forte tablets are used for the same purpose. They are used to treat nerve pain. They are also made by the same company. Read Also :  All about Neurovit tablet for nerve pain Difference Between Neurovit And Neurovit Forte Tablet 1. The major is the strength of the ingredients. Neurovit tablet contains lower strength than Neurovit forte tablet. Neurovit tablet contains Thiamine Mononitrate 97.00 mg; Pyridoxine HCl 50.00 mg; Cyanocobalamin 100.00 mcg. On the other hand, Neurovit forte contain Thiamine Mononitrate (Vit B1) 242.5 mg; Pyridoxine HCl (Vit B6) 250.0 mg; Cyanocobalamin (Vit B12) 1.0 mg 2. The dosage may also be used to differentiate them. While Neurovit tablet is administered orally one (1) Orr two (2) tablet daily, Neurovit forte tablet is given...

Hovid Neurovit forte tablet is manufactured with pharmaceutical standards. It contains the 3 main vitamins B, B1 (thiamine), B6 (Pyridoxine) and B12 (Cyanocobalamin). Neurovit forte Neurovit Forte Benefits And Function Cyanocobalamin acts as a coenzyme for fat and carbohydrate metabolism. It is essential for growth, cell replication, haematopoiesis and nucleoprotein and myelin synthesis. Thiamine pyrophosphate and pyridoxal phosphate, the physiologically active forms of thiamine and pyridoxine respectively, act as coenzymes for various metabolic functions affecting protein, carbohydrate and lipid metabolism. Read Also :  Treatment of pain using drugs The B vitamins are readily absorbed orally except in malabsorption syndromes, metabolised in the liver and excreted via the kidneys. Nuetovit Indication And Use For treatment of peripheral neuropathy and neuralgias. Neurovit Dosage Adults: Oral, 1 tablet daily; or as directed. Children: As directed by the physician. Note: The informati...

Hovid Neurovit is manufactured with pharmaceutical standards. It contains the 3 main vitamins B, B1 (thiamine), B6 (Pyridoxine) and B12 (Cyanocobalamin). Neurovit tablet Benefits And Function Of Neurovit They help improve nerves functions, relieving pain and tingling sensation at the fingers and toes, in diabetics and elderly people. Vitamin B1, B6 and B12 are key vitamins that helps in nerve conduction and reduces sensation of pain, tingling and numbness at the extremities like fingers and toes. Read Also:   Top pharmacy company in Nigeria These problems usually happens when there are insufficient blood flows to the fingers and toes, or due to compression of nerves leading to the extremities. These are common conditions happened to: Diabetics - due to reduction of nerves functions, as a results of high sugar levels in the blood, leading to damages on the nerves Elderly or senior - lack of blood supply to the extremities, cause by inefficient blood floor or anemic condition Nerves ...

Fijk is a polyherbal formulation made from various ethnomedicinal plants. It is marketed in Nigeria by Okooloyun Worldwide Nigeria Limited. According to the Fijk leaflet, the herb is prepared from a mixture of different medicinal plants including Cassia alata, Citrus Medica var acida, Aloe vera, Cassia angustifolia and Cassia siamea. Read Also:  Fijk side effects Fijk flusher Fijk herbal mixture is acclaimed by its producers to have several medicinal benefits. This must have contributed to the wide patronage and consumption among the Nigerian populace. According to the Fijk label, the herbal remedy is indicated for treatments of several ailments which include obesity, diabetes, sexual improvement, menstruation pains, infertility, high blood pressure, crawling sensation, and malaria, amongst others. There are scientific reports on the medicinal relevance of the individual plant constituents of the Fijk mixture. However, there is no empirical data to support claims of medicinal benef...

Fijk flusher Fijk flusher was produced and formulated in the year 1998. It was then used as treatment of different forms of disease. Manufacturers claim there were abundant testimonies proving its efficacy. In 2003, an improvement was made on it by adding some other active ingredients to enhance its efficacy and potency. Read Also:   Benefits of fijk flusher Fijk Flusher Side Effect According to the manufacturer, there are no known side effects after long term usage with fijk flusher. However, diarrhoea has side effects. That is while those already experiencing diarrhoea should avoid fijk flusher. This includes those who have cholera.

Fijk flusher was produced and formulated in the year 1998. It was then used as treatment of different forms of disease. Manufacturers claim there were abundant testimonies proving its efficacy. In 2003, an improvement was made on it by adding some other active ingredients to enhance its efficacy and potency. Fijk Fijk Flusher For Pregnancy Fijk flusher promises sexual improvement in both male and females. For females, it is used for irregular menstruation and for fertility. For men, it is used for premature ejaculation. Read Also:   Benefits of STC30 However, the patient information leaflet clearly stated that fijk flusher should be avoided in pregnancy. And the label on the package said not to be taken during the first three months of pregnancy. Whatever the case, the ingredients have not been shown to affect pregnancy. But pregnant women should stay off alcohol of any type or quantity. Fijk flusher can harm the unborn child in many ways we cannot know for now. Read Also:   ...